Balancing the antibacterial and osteogenic effects of double-layer TiO<sub>2</sub> nanotubes loaded with silver nanoparticles for the osseointegration of implants
Lei Sun, Xuzhuo Chen, Ruiguo Chen, Zhibo Ji, Hai-Zhang Mu, Chun Liu, Jinlan Yu, Jiarong Wang, Rong Xia, Shanyong Zhang, Yin Xu, Kun Ma, Lunguo Xia
Abstract
, DNT-Ag8 promoted bone-implant osseointegration in a beagle mandibular tooth loss model. This study demonstrated that the uniform loading of small-diameter silver nanoparticles using a honeycomb bilayer nanotube template structure is a promising method for modifying titanium surfaces to improve both bacteriostasis and osseointegration.
Topics & Concepts
Silver nanoparticleOsseointegrationAntibacterial activityIn vivoMaterials scienceNanoparticleAdhesionAbsorbanceChemistryNanotechnologyNuclear chemistryImplantBacteriaComposite materialChromatographyMedicineGeneticsSurgeryBiotechnologyBiologyBone Tissue Engineering MaterialsDental Implant Techniques and OutcomesGraphene and Nanomaterials Applications