New spectrum of COVID-19 manifestations in children: Kawasaki-like syndrome and hyperinflammatory response
Sirada Panupattanapong, Elizabeth B. Brooks
Abstract
In April 2020, data began emerging on Kawasaki-like syndrome and hyperinflammatory response in children with COVID-19. Since then, much has been published on the presentation of COVID-19 in pediatric patients, including its association with Kawasaki disease and the multisystem inflammatory syndrome in children (MIS-C). However, questions still remain regarding the risk factors, pathogenesis, prognosis, and specific therapy for these manifestations of COVID-19.
Topics & Concepts
MedicineKawasaki diseaseCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakPediatricsPathogenesisPresentation (obstetrics)DiseaseImmunologyInternal medicineVirologySurgeryInfectious disease (medical specialty)OutbreakArteryKawasaki Disease and Coronary ComplicationsMechanical Circulatory Support DevicesCoronary Artery Anomalies