Quinol-containing ligands enable high superoxide dismutase activity by modulating coordination number, charge, oxidation states and stability of manganese complexes throughout redox cycling
Laura Senft, Jamonica L. Moore, Alicja Franke, Katherine R. Fisher, Andreas Scheitler, Achim Zahl, Ralph Puchta, Dominik Fehn, Sidney Ison, Safaa Sader, Ivana Ivanović‐Burmazović, Christian R. Goldsmith
Abstract
Manganese complexes with polydentate quinol-containing ligands are found to catalyze the degradation of superoxide through inner-sphere mechanisms. The redox activity of the ligand stabilizes higher-valent manganese species.
Topics & Concepts
ManganeseChemistryRedoxDenticitySuperoxideLigand (biochemistry)Superoxide dismutaseCoordination sphereOxidation statePhotochemistryInorganic chemistryBiochemistryReceptorMetalEnzymeCatalysisOrganic chemistryMetal-Catalyzed Oxygenation MechanismsLanthanide and Transition Metal ComplexesMetal complexes synthesis and properties