Dioscin Alleviates Periodontitis by Inhibiting NLRP3 Inflammasome Activation via Regulation of K<sup>+</sup> Homeostasis and Mitochondrial Function
Xue Jiang, Xinxin Ding, Jianxu Wei, Xiaolei Lv, Yi Zhang, Yijie Yang, Hongchang Lai, Xiaomeng Zhang
Abstract
efflux-mtROS-ox-mtDNA pathway, holding the potential to treat periodontitis and other NLRP3-driven inflammatory diseases.
Topics & Concepts
InflammasomePeriodontitisInflammationChemistryReactive oxygen speciesEffluxPharmacologyImmunologyCell biologyBiologyMedicineBiochemistryInternal medicineInflammasome and immune disordersImmune Response and Inflammationinterferon and immune responses