Defects in Protein Folding and/or Quality Control Cause Protein Aggregation in the Endoplasmic Reticulum
Juthakorn Poothong, Insook Jang, Randal J. Kaufman
Topics & Concepts
Endoplasmic reticulumEndoplasmic-reticulum-associated protein degradationUnfolded protein responseProtein foldingProtein aggregationProteostasisChaperone (clinical)Cell biologyBiologyAggresomeER retentionProtein degradationBiochemistryAutophagyMutantApoptosisMedicineGenePathologyEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyMicrobial Inactivation Methods