Zanthoxylum armatum DC. extract induces liver injury via autophagy suppression and oxidative damage by activation of mTOR/ULK1 pathway
Yan Huang, Jialuo Jiang, Wenlin Wang, Jiafu Guo, Nannan Yang, Jian Zhang, Qiuyan Liu, Yan Chen, Tingting Hu, Chaolong Rao
Topics & Concepts
Aspartate transaminaseSuperoxide dismutaseAlanine transaminaseGlutathioneAutophagyPI3K/AKT/mTOR pathwayReactive oxygen speciesMalondialdehydeLiver injuryPharmacologyIn vivoViability assayBiologyChemistryBiochemistryAlkaline phosphataseOxidative stressEndocrinologySignal transductionCellApoptosisEnzymeBiotechnologyGenomics, phytochemicals, and oxidative stressAutophagy in Disease and TherapyBerberine and alkaloids research