Discovery of predictive biomarkers for cancer therapy through computational approaches
Xin Wang, Julia Nguyen, Kristen Nader, Mitro Miihkinen, Patrick D. Wall, Akshat Singhal, Philippe L. Bédard, Trey Ideker, Tero Aittokallio, Benjamin Haibe‐Kains
Topics & Concepts
MedicineBiomarker discoveryPrecision medicineClinical trialBiomarkerComputational biologyPersonalized medicineBioinformaticsPredictive modellingDrug developmentCancer biomarkersDrug discoveryOncologyEfficacyCancer treatmentPredictive valueComputational modelCancerMolecular biomarkersMachine learningCancer therapyMEDLINEDrugRobustness (evolution)Targeted therapyFeature selectionCancer drugsDrug repositioningClinical efficacyInternal medicineTranscriptomePredictive markerPredictive value of testsGene expression and cancer classificationRadiomics and Machine Learning in Medical ImagingStatistical Methods in Clinical Trials