Enhanced ferroptosis therapy with a “nano-destructor” by disrupting intracellular redox and iron homeostasis
Ting Song, Geng Yang, Hanxi Zhang, Mengyue Li, Wanyi Zhou, Chuan Zheng, Fengming You, Chunhui Wu, Yiyao Liu, Hong Yang, Hong Yang
Topics & Concepts
HomeostasisChemistryIntracellularGPX4GlutathioneCell biologyProgrammed cell deathReactive oxygen speciesAutophagyRedoxBiophysicsBiochemistryGlutathione peroxidaseApoptosisBiologyEnzymeOrganic chemistryFerroptosis and cancer prognosisExtracellular vesicles in diseaseNanoplatforms for cancer theranostics