Moving towards a Treatable Traits model of care for the management of obstructive airways diseases
Àlvar Agustí, Neil Barnes, Álvaro A. Cruz, Peter G. Gibson, Liam G. Heaney, Hiromasa Inoue, David Leather, Fernando J. Martínez, Vanessa M. McDonald, John Oppenheimer, Alberto Papi, Ian Pavord, Mike Thomas, Samantha Walker, Louisa Yates
Abstract
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airways diseases. Both are complex and heterogeneous. Traditionally, clinical guidelines have advocated a stepwise approach to pharmacotherapy of asthma and COPD, but there is increasing realization that both require a more personalized and precise management approach. To this end, a management strategy based on the so-called Treatable Traits has been proposed. Emerging evidence suggests that this model improves relevant outcomes in patients with chronic airway diseases but further research is needed to guide implementation. This review discusses the challenges, opportunities, and hurdles that its implementation will have to face.