Integrated metabolomic and transcriptomic analysis identifies benzo[a]pyrene-induced characteristic metabolic reprogramming during accumulation of lipids and reactive oxygen species in macrophages
Guozhu Ye, Wenjia Lu, Luyun Zhang, Han Gao, Xu Liao, Xu Zhang, Han Zhang, Jinsheng Chen, Qiansheng Huang
Topics & Concepts
BiochemistryChemistryReactive oxygen speciesPentose phosphate pathwayMetabolic pathwayOxidative stressMetabolismGlycolysisMetabolomics and Mass Spectrometry StudiesAdipose Tissue and MetabolismImmune cells in cancer