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Trend analysis of clinical aspects of congenital syphilis in Brazil, 2009–2018

Bruno Quintela Souza de Moraes, Alexya de Oliveira Feitosa, Roberta Albuquerque Wanderley, Michael Ferreira Machado

2021Revista da Associação Médica Brasileira15 citationsDOIOpen Access PDF

Abstract

INTRODUCTION: Congenital syphilis is caused by the vertical transmission of bacteria, Treponema pallidum, from nontreated or inappropriately treated pregnant to the fetus. OBJECTIVE: To evaluate the clinical aspects of Congenital syphilis in Brazil, between 2009-2018. METHOD: It is an analytical cross-sectional study whose data were collected from the Department of Chronical Conditions and Sexually Transmitted Infections of Brazilian Health Ministry. Clinical variables were analyzed using the software Joinpoint Regression, which makes a segmented linear regression. RESULTS: In the study period, 156,969 cases of Congenital syphilis and 1642 deaths by this disease were reported. The trend analysis indicates growing in diagnosis of maternal syphilis during prenatal care, appropriate treatment of pregnant, realization of prenatal care, maternal partner treatment, diagnosis of syphilis in children under seven days, and diagnosis of recent syphilis. CONCLUSIONS: Although the trend analysis presents relative improvement in Congenital syphilis panorama in Brazil, the disease still related to high numbers of evitable perinatal morbidity and mortality. Therefore, the prenatal assistance with quality is fundamental to have a possible change in this field in the country.

Topics & Concepts

Congenital syphilisSyphilisMedicinePrenatal careSexually transmitted diseasePediatricsTransmission (telecommunications)Christian ministryDiseasePregnancyObstetricsEnvironmental healthFamily medicinePopulationInternal medicineHuman immunodeficiency virus (HIV)PhilosophyTheologyElectrical engineeringEngineeringBiologyGeneticsSyphilis Diagnosis and TreatmentMaternal and Neonatal HealthcareWomen's cancer prevention and management