Electrochemical <i>S</i>-vinylation of sulfinamides with β-bromostyrenes
Yaseen Hussain, Ivan Sliusarevskyi, Claire Empel, Magnus Rueping, René M. Koenigs
Abstract
radical cross-coupling of sulfonimidoyl and styryl radicals, generated from sulfinamides and bromostyrenes. This approach enables the efficient synthesis of vinyl sulfoximines, including bioactive-tethered derivatives, in moderate to good yields.
Topics & Concepts
ElectrochemistryRadicalChemistryCombinatorial chemistryOrganic chemistryElectrodePhysical chemistrySulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsRadical Photochemical Reactions