Electric-field-induced coupling of aryl iodides with a nickel(0) complex
Nicholas M. Orchanian, S. Guizzo, Michael L. Steigerwald, Colin Nuckolls, Latha Venkataraman
Abstract
The formation of carbon-carbon bonds with transition metal reagents serves as a cornerstone of organic synthesis. Here, we show that the reactivity of an otherwise kinetically inert transition metal complex can be induced by an external electric field to affect a coupling reaction. These results highlight the importance of electric field effects in reaction chemistry and offers a new strategy to modulate organometallic reactivity.
Topics & Concepts
Reactivity (psychology)ReagentArylChemistryInertNickelTransition metalElectric fieldCoupling reactionOrganometallic chemistryCoupling (piping)Field (mathematics)PhotochemistryCombinatorial chemistryOrganic chemistryCatalysisMaterials scienceAlkylPathologyPure mathematicsMathematicsMedicineQuantum mechanicsMetallurgyPhysicsAlternative medicineMolecular Junctions and NanostructuresCatalytic Cross-Coupling ReactionsRadical Photochemical Reactions