3D chromatin maps of the human pancreas reveal lineage-specific regulatory architecture of T2D risk
Chun Su, Long Gao, Catherine Lee May, James A. Pippin, Keith D. Boehm, Michelle Lee, Chengyang Liu, Matthew C. Pahl, Maria L. Golson, Ali Naji, Struan F.A. Grant, Andrew D. Wells, Klaus H. Kaestner
Topics & Concepts
ChromatinBiologyEpigenomicsRegulatory sequenceGeneticsCell typeGeneComputational biologyGenome-wide association studyTranscriptomeChIA-PETRegulation of gene expressionChromatin remodelingGene expressionCellDNA methylationSingle-nucleotide polymorphismGenotypeSingle-cell and spatial transcriptomicsPancreatic function and diabetesPancreatic and Hepatic Oncology Research