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Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells

Ruth Magaye, Feby Savira, Hua Yue, Xin Xiong, Li Huang, Christopher M. Reid, Bernard L. Flynn, David M. Kaye, Danny Liew, Bing H. Wang

2021The International Journal of Biochemistry & Cell Biology35 citationsDOIOpen Access PDF

Topics & Concepts

PI3K/AKT/mTOR pathwayProtein kinase BCell biologyMyocyteRPTORBiologySphingosine-1-phosphateSignal transductionEndocrinologyInternal medicineChemistrySphingosineBiochemistryMedicineReceptorSphingolipid Metabolism and SignalingPI3K/AKT/mTOR signaling in cancerCellular transport and secretion
Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells | Litcius