Geniposide effectively safeguards HT22 cells against Aβ-induced damage by activating mitophagy via the PINK1/Parkin signaling pathway
Jiaxi Ye, Jiaying Wu, Liang Ai, Min Zhu, Yun Li, Dong Yin, Qihui Huang
Topics & Concepts
ParkinPINK1MitophagyChemistryOxidative stressDownregulation and upregulationCell biologyReactive oxygen speciesAutophagyMitochondrionPharmacologyApoptosisBiochemistryBiologyParkinson's diseaseMedicineInternal medicineDiseaseGeneAutophagy in Disease and TherapyAlzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments