Fabrication of green poly(vinyl alcohol) nanofibers using natural deep eutectic solvent for fast-dissolving drug delivery
Qingmiao Zhang, Zhuangsheng Lin, Wenkun Zhang, Ting Huang, Jingjing Jiang, Yu Ren, Ruiqi Zhang, Wen Li, Xiaoli Zhang, Qin Tu
Abstract
study proved that the PVA-DES-honey nanofibers accelerated the wound healing process, and they improved the wound healing rate on rat skin to 85.2% after 6 days of surgery, when compared to the control PVA (68.2%) and PVA-DES (76.3%) nanofibers. Overall, the nanofiber materials reported in our study showed potential as a green and biocompatible fast-dissolving drug delivery system and can be used for pharmaceutical fields, such as antibacterial wound dressing and oral ulcer stickers.
Topics & Concepts
NanofiberVinyl alcoholDissolutionDrug deliveryDeep eutectic solventMaterials sciencePolyvinyl alcoholDrug carrierChemistryNuclear chemistryEutectic systemNanotechnologyOrganic chemistryComposite materialMicrostructurePolymerElectrospun Nanofibers in Biomedical ApplicationsAdvanced Sensor and Energy Harvesting MaterialsPolymer composites and self-healing