Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells
Rui Ding, Xiaoyan Yu, Zhilin Hu, Yu Dong, Haiyan Huang, Yuerong Zhang, Qiaoqiao Han, Zhiyu Ni, Ren Zhao, Youqiong Ye, Qiang Zou
Topics & Concepts
BiologyRNA splicingCTLA-4RNAAlternative splicingCancer researchCell biologyGeneMessenger RNAGeneticsImmune systemT cellImmune Cell Function and InteractionT-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers