Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML
Elizabeth Heyes, Luisa Schmidt, Gabriele Manhart, Thomas Eder, Ludovica Proietti, Florian Grebien
Topics & Concepts
CEBPABiologyGene knockdownEpigeneticsTranscription factorMyeloid leukemiaCcaat-enhancer-binding proteinsRNA interferenceGeneCancer researchMyeloidEffectorGeneticsMolecular biologyCell biologyRNANuclear proteinAcute Myeloid Leukemia ResearchProtein Degradation and InhibitorsEpigenetics and DNA Methylation