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The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation

Bruno Caetano Trindade, Simona Ceglia, Alyssa Berthelette, Fiona Raso, Kelsey Howley, Jagan Muppidi, Andrea Reboldi

2021Immunity76 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCholesterolGerminal centerImmune systemCellular differentiationEndocrinologyB cellInternal medicineAntibodyCell biologyImmunologyBiochemistryGeneMedicineCholesterol and Lipid MetabolismImmune Cell Function and InteractionT-cell and B-cell Immunology
The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation | Litcius