Extensively Drug-Resistant Typhoid Fever in the United States
Michael Hughes, Meseret G. Birhane, Layne Dorough, Jared Reynolds, Hayat Caidi, Kaitlin A. Tagg, Caroline M Snyder, Alexander T. Yu, Shana M Altman, Michelle M. Boyle, Deepam Thomas, Amy E Robbins, HaeNa A Waechter, Irina Cody, Eric D. Mintz, Bruce Gutelius, Gayle Langley, Louise Francois Watkins
Abstract
Cases of extensively drug-resistant (XDR) typhoid fever have been reported in the United States among patients who did not travel internationally. Clinicians should consider if and where the patient traveled when selecting empiric treatment for typhoid fever. XDR typhoid fever should be treated with a carbapenem, azithromycin, or both.
Topics & Concepts
Typhoid feverMedicineAzithromycinEnteric feverEmpiric therapyDrugIntensive care medicinePediatricsVirologyAntibioticsAlternative medicineMicrobiologyPharmacologyBiologyPathologySalmonella and Campylobacter epidemiologyInfectious Encephalopathies and EncephalitisVibrio bacteria research studies