Detection of a Novel African Swine Fever Virus with Three Large-Fragment Deletions in Genome, China
Yankuo Sun, Zhiying Xu, Han Gao, Sijia Xu, Jing Liu, Jiabao Xing, Qiyuan Kuang, Yang Chen, Heng Wang, Guihong Zhang
Abstract
African swine fever virus (ASFV) has been circulating in China for 5 years, and low virulent strains with changes in the genome have been reported. Nevertheless, there is still a lack of knowledge about the epidemic strains at the whole-genome level. This study reported a novel strain and further analyzed its genomic and biological characteristics. In addition, our study also suggests that whole-genome sequencing plays a key role in the epidemiology investigation of ASFV variations.
Topics & Concepts
African swine fever virusGenomeBiologyVirologyVirusVirulenceStrain (injury)Whole genome sequencingGeneticsPhenotypeGeneAnatomyAnimal Disease Management and EpidemiologyT-cell and Retrovirus StudiesVector-Borne Animal Diseases