Interleukin 6 trans-signaling is a critical driver of lung allograft fibrosis
David Wheeler, Keizo Misumi, Natalie Walker, Ragini Vittal, M.P. Combs, Yoshiro Aoki, Russell R. Braeuer, Vibha N. Lama
Topics & Concepts
MedicineFibrosisBronchoalveolar lavageDownregulation and upregulationInflammationMesenchymal stem cellPathogenesisCancer researchPeripheral blood mononuclear cellLungInterleukinSTAT3Pulmonary fibrosisImmunologyCrosstalkMyofibroblastPhosphorylationCytokinePathologyInternal medicineBiologyCell biologyGenePhysicsOpticsBiochemistryIn vitroTransplantation: Methods and OutcomesInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisViral Infections and Immunology Research