Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis
Duanyang Zhai, Yu Zhou, Xiaying Kuang, Fangyuan Shao, Tiantian Zhen, Ying Lin, Qing Wang, Nan Shao
Abstract
Our study revealed a novel lnc NR2F1-AS1/miR-25-3p/ZEB2 axis in BC metastasis and that lnc NR2F1-AS1 may serve as a potential therapeutic target for BC metastasis.
Topics & Concepts
Gene knockdownMetastasisCancer researchmicroRNABiologyLong non-coding RNABreast cancerCompeting endogenous RNACancerCell cultureRNAGeneGeneticsCancer-related molecular mechanisms researchCircular RNAs in diseasesMicroRNA in disease regulation