Development of oral aprepitant-loaded chitosan–polyethylene glycol-coated cyclodextrin nanocapsules: formulation, characterization, and pharmacokinetic evaluation
Nazlı Erdoğar, Safiye Akkın, Thorbjørn Terndrup Nielsen, Esin Özçelebi, Batuhan Erdoğdu, Emirhan Nemutlu, Alper B. İskit, Erem Bilensoy
Topics & Concepts
NanocapsulesAprepitantPolyethylene glycolChitosanPharmacokineticsCyclodextrinPharmacologyChemistryChromatographyMaterials scienceMedicineNanotechnologyOrganic chemistryNanoparticleChemotherapySurgeryAntiemeticDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsNanoparticle-Based Drug Delivery