Preparation of cerium molybdates and their antiviral activity against bacteriophage Φ6 and SARS-CoV-2
Takuro Ito, Kayano Sunada, Takeshi Nagai, Hitoshi Ishiguro, Ryuichi Nakano, Yuki Suzuki, Akiyo Nakano, Hisakazu Yano, Toshihiro Isobe, Sachiko Matsushita, Akira Nakajima
Abstract
Two cerium molybdates (Ce2Mo3O12 and γ-Ce2Mo3O13) were prepared using either polymerizable complex method or hydrothermal process. The obtained powders were almost single-phase with different cerium valence. Both samples were found to have antiviral activity against bacteriophage Φ6. Especially, γ-Ce2Mo3O13 exhibited high antiviral activity against both bacteriophage Φ6 and SARS-CoV-2 coronavirus, which causes COVID-19. A synergetic effect of Ce and molybdate ion was inferred along with the specific surface area as key factors for antiviral activity.
Topics & Concepts
CeriumMolybdateBacteriophageMaterials scienceHydrothermal circulationBiologyEscherichia coliBiochemistryMetallurgyPaleontologyGeneAdvanced Nanomaterials in CatalysisPolyoxometalates: Synthesis and ApplicationsInfectious Encephalopathies and Encephalitis