A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope
Laura A. VanBlargan, Lucas J. Adams, Zhuoming Liu, Rita E. Chen, Pavlo Gilchuk, Saravanan Raju, Brittany Smith, Haiyan Zhao, James Brett Case, Emma S. Winkler, Bradley Whitener, Lindsay Droit, Ishmael D. Aziati, Traci L. Bricker, Astha Joshi, Pei‐Yong Shi, Adrian Creanga, Amarendra Pegu, Scott A. Handley, David Wang, Adrianus C. M. Boon, James E. Crowe, Sean P. J. Whelan, Daved H. Fremont, Michael Diamond
Topics & Concepts
EpitopeBiologyVirologyMonoclonal antibodyAntibodyNeutralizing antibodyReceptorCoronavirusVirusEpitope mappingNeutralizationImmunologyCoronavirus disease 2019 (COVID-19)GeneticsInfectious disease (medical specialty)MedicineDiseasePathologySARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologyAnimal Virus Infections Studies