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Fibrin exposure triggers αIIbβ3‐independent platelet aggregate formation, ADAM10 activity and glycoprotein VI shedding in a charge‐dependent manner

Samantha J. Montague, Sarah M. Hicks, Christine S.M. Lee, Lucy A. Coupland, Christopher R. Parish, Woei Ming Lee, Robert K. Andrews, Elizabeth E. Gardiner

2020Journal of Thrombosis and Haemostasis21 citationsDOIOpen Access PDF

Topics & Concepts

GPVIFibrinChemistryPlateletPlatelet activationDisintegrinCell biologyPlatelet membrane glycoproteinADAM10MetalloproteinaseBiochemistryBiophysicsImmunologyGlycoproteinBiologyMatrix metalloproteinasePlatelet Disorders and TreatmentsBlood transfusion and managementSepsis Diagnosis and Treatment
Fibrin exposure triggers αIIbβ3‐independent platelet aggregate formation, ADAM10 activity and glycoprotein VI shedding in a charge‐dependent manner | Litcius