BI-1 ameliorates myocardial injury by activating the mitochondrial unfolded protein response and FUNDC1-related mitophagy in cardiorenal syndrome type 3
Jin Wang, Xiaohua Wang, Wenjuan Du, Zhe Xue, Wei Huang, Zhenpeng Guan, Hongyu Wang
Topics & Concepts
MitophagyDownregulation and upregulationMitochondrionUnfolded protein responseCell biologyATF6Small hairpin RNAIntegrated stress responseMitochondrial ROSAutophagyReperfusion injuryChemistryInternal medicineEndocrinologyApoptosisBiologyMedicineGene knockdownIschemiaMessenger RNAEndoplasmic reticulumBiochemistryTranslation (biology)GeneAutophagy in Disease and TherapyAdvanced Glycation End Products researchAdvanced Battery Technologies Research