Dissemination of circulating tumor cells at night: role of sleep or circadian rhythm?
Yves Dauvilliers, Frédéric Thomas, Catherine Alix‐Panabières
Abstract
The analysis of blood for circulating tumor cells (CTCs) called liquid biopsy has opened new avenues for cancer diagnostic and management, as well as the comprehension of the metastatic cascade [1]. As metastasis is responsible for about 90% of cancer deaths [2], it is of utmost importance to decrease the survival of CTCs, mostly to target specifically the metastasis-competent CTCs while they are reaching distant organs
Topics & Concepts
Circadian rhythmBiologyHuman geneticsSleep (system call)Circadian clockRhythmGenome BiologyNeuroscienceGeneticsInternal medicineGenomeGeneGenomicsMedicineOperating systemComputer scienceCircadian rhythm and melatoninDietary Effects on HealthSleep and Wakefulness Research