An Overview on Topical Administration of Carotenoids and Coenzyme Q10 Loaded in Lipid Nanoparticles
Luciana de Souza Guedes, Renata Miliani Martinez, Nádia Araci Bou‐Chacra, Maria Valéria Robles Velasco, Catarina Rosado, André Rolim Baby
Abstract
Carotenoids and coenzyme Q10 are naturally occurring antioxidant compounds that are also found in human skin. These bioactive compounds have been the focus of considerable research due to their antioxidant, anti-inflammatory, and photoprotective properties. In this review, the current state of the art in the encapsulation of carotenoids and coenzyme Q10 in lipid nanoparticles to improve their bioavailability, chemical stability, and skin absorption is discussed. Additionally, the main findings are highlighted on the cytotoxic and photoprotective effects of these systems in the skin.
Topics & Concepts
Coenzyme Q10CarotenoidBioavailabilityAntioxidantChemistryHuman skinSolid lipid nanoparticlePharmacologyBiochemistryMedicineDrug deliveryOrganic chemistryBiologyGeneticsAntioxidant Activity and Oxidative StressFree Radicals and AntioxidantsBee Products Chemical Analysis