Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy
Yaw Opoku‐Damoah, Run Zhang, Hang T. Ta, Zhi Ping Xu
Abstract
A reliable approach is developed to formulate a targeted lipid-coated nanomedicine based on UCNP and co-loaded with CO-prodrug and vitamin E, which can convert NIR light to UV photon to release CO for synergistical cancer therapy with vitamin E.
Topics & Concepts
NanomedicineProdrugDrugChemistryPhotodynamic therapyVitaminCancerCarbon monoxidePharmacologyCancer researchNanotechnologyCombinatorial chemistryMedicineBiochemistryCatalysisMaterials scienceNanoparticleInternal medicineOrganic chemistryHeme Oxygenase-1 and Carbon MonoxideNanoplatforms for cancer theranosticsHemoglobin structure and function