Reversing tumor multidrug resistance with a catalytically active covalent organic framework
Peng Gao, Teng Zheng, Bingjie Cui, Xiaohan Liu, Wei Pan, Na Li, Bo Tang
Abstract
A catalytically active nanoscale covalent organic framework based on Fe-porphyrin was developed for reversing tumor multi-drug resistance.
Topics & Concepts
Multiple drug resistanceCovalent bondIntracellularIn vivoCovalent organic frameworkChemistryCatalysisIn vitroReversingDrug resistanceCombinatorial chemistryBiophysicsBiochemistryMaterials scienceOrganic chemistryBiologyAntibioticsMicrobiologyBiotechnologyComposite materialNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryMetal-Organic Frameworks: Synthesis and Applications