Intranasal fosphenytoin: The promise of phosphate esters in nose-to-brain delivery of poorly soluble drugs
Patrícia C. Pires, Liliana T. Santos, Márcio Rodrigues, Gilberto Alves, Adriana O. Santos
Topics & Concepts
Nasal administrationProdrugBioavailabilityPharmacologyDrug deliveryChemistryDosage formPharmacokineticsPhenytoinAnticonvulsantDrugMedicineOrganic chemistryEpilepsyPsychiatryAdvanced Drug Delivery SystemsEpilepsy research and treatmentPharmacological Effects and Toxicity Studies