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Far-field super-resolution chemical microscopy

Mingwei Tang, Yubing Han, Danchen Jia, Qing Yang, Ji‐Xin Cheng

2023Light Science & Applications27 citationsDOIOpen Access PDF

Abstract

Far-field chemical microscopy providing molecular electronic or vibrational fingerprint information opens a new window for the study of three-dimensional biological, material, and chemical systems. Chemical microscopy provides a nondestructive way of chemical identification without exterior labels. However, the diffraction limit of optics hindered it from discovering more details under the resolution limit. Recent development of super-resolution techniques gives enlightenment to open this door behind far-field chemical microscopy. Here, we review recent advances that have pushed the boundary of far-field chemical microscopy in terms of spatial resolution. We further highlight applications in biomedical research, material characterization, environmental study, cultural heritage conservation, and integrated chip inspection.

Topics & Concepts

Chemical imagingMicroscopyResolution (logic)Near-field scanning optical microscopeNanotechnologyOptical microscopeOpticsMaterials scienceComputer sciencePhysicsHyperspectral imagingArtificial intelligenceScanning electron microscopeNear-Field Optical MicroscopyAdvanced Fluorescence Microscopy TechniquesIntegrated Circuits and Semiconductor Failure Analysis
Far-field super-resolution chemical microscopy | Litcius