HDAC3 promotes pulmonary fibrosis by activating NOTCH1 and STAT1 signaling and up-regulating inflammasome components AIM2 and ASC
Qing Yin Zheng, Yao Lei, Shan Hui, Ming Tong, Lihui Liang
Topics & Concepts
HDAC3STAT1InflammasomeSTAT3STAT proteinCancer researchSignal transductionProinflammatory cytokineChemistryPulmonary fibrosisJanus kinaseBiologyFibrosisInflammationCell biologyImmunologyHistoneMedicinePathologyBiochemistryHistone deacetylaseGeneInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisPulmonary Hypertension Research and TreatmentsChronic Obstructive Pulmonary Disease (COPD) Research