Bioconversion of methane to cadaverine and lysine using an engineered type II methanotroph, <i>Methylosinus trichosporium</i> OB3b
Nguyễn Thị Hoài Thu, Ok Kyung Lee, Sanzhar Naizabekov, Eun Yeol Lee
Abstract
Cadaverine is an important monomer used for the production of bio-polyamides. Based on the genome-scale metabolic model of type II methanotroph, iMsOB3b1_cadaverine, we engineered <italic>Methylosinus trichosporium</italic> OB3b to produce cadaverine from methane.
Topics & Concepts
CadaverineMethanotrophBioconversionChemistrySIRT2BiochemistryEnzymeAnaerobic oxidation of methaneFermentationCatalysisSirtuinPutrescineNAD+ kinaseMicrobial metabolism and enzyme functionBiofuel production and bioconversionAnaerobic Digestion and Biogas Production