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‘Off-the-shelf’ allogeneic CAR T cells: development and challenges

Stéphane Depil, Philippe Duchâteau, Stephan A. Grupp, G J Mufti, Laurent Poirot

2020Nature Reviews Drug Discovery1,186 citationsDOI

Topics & Concepts

Chimeric antigen receptorImmune systemImmunologyImmunotherapyT cellAntigenGraft-versus-host diseaseMedicineCell therapyDiseaseCancer researchBiologyStem cellInternal medicineCell biologyCAR-T cell therapy researchNanowire Synthesis and ApplicationsViral Infectious Diseases and Gene Expression in Insects
‘Off-the-shelf’ allogeneic CAR T cells: development and challenges | Litcius