Allosteric inhibitors of the main protease of SARS-CoV-2
Subodh Kumar Samrat, Jimin Xu, Xuping Xie, Eleonora Gianti, Haiying Chen, Jing Zou, Jason G. Pattis, Khaled M. Elokely, Hyun Lee, Zhong Li, Michael L. Klein, Pei‐Yong Shi, Jia Zhou, Hongmin Li
Topics & Concepts
Allosteric regulationChemistryEnzymeProteaseDocking (animal)BiochemistryIC50Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PharmacologyBiologyCoronavirus disease 2019 (COVID-19)In vitroMedicineInfectious disease (medical specialty)NursingDiseasePathologySARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery Methodsinterferon and immune responses