Structural effect of NIR-II absorbing charge transfer complexes and its application on cysteine-depletion mediated ferroptosis and phototherapy
Wei Ge, Yatao Xu, Chao Liu, Wenjng Xu, Yewei Zhang, Weili Si, Wenli Zhao, Changjin Ou, Xiaochen Dong
Abstract
NIR-II absorbing charge transfer complexes consisting of electron-deficient F4TCNQ and electron-rich donors are reported, which presented great anti-tumor performance with NIR-II PAI/ferroptosis/phototherapy effects.
Topics & Concepts
Charge (physics)CysteineElectron transferElectronMaterials sciencePhotochemistryBiophysicsChemistryOptoelectronicsNanotechnologyBiochemistryBiologyPhysicsEnzymeQuantum mechanicsNanoplatforms for cancer theranosticsSulfur Compounds in BiologyNanocluster Synthesis and Applications