Reactivity Trends with Borylalkyl Copper(I) Species
Macarena Corro, Oriol Salvadó, Sara González, Paula Dominguez‐Molano, Elena Fernández
Abstract
Abstract The renaissance on the application of gem ‐diborylalkanes from 2010, has allowed the conquest of new synthetic application towards C−C and C−N bond formation. The activation of gem ‐diborylalkanes by Cu(I) catalysts, generates active borylalky copper(I) species that are able to trap several electrophilic reagents, in an efficient way. In addition, the modification of Cu(I) complexes with chiral ligands, induces asymmetric platforms towards the synthesis of enantioenriched organoboron compounds.
Topics & Concepts
ChemistryElectrophileReagentReactivity (psychology)CopperCatalysisCombinatorial chemistryThe RenaissanceOrganometallic chemistryOrganoboron compoundsCONQUESTOrganic chemistryHistoryArt historyPathologyArtAlternative medicineAncient historyMedicineOrganoboron and organosilicon chemistryCatalytic Cross-Coupling ReactionsAsymmetric Synthesis and Catalysis