Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review
Arwa A. Al-Qahtani, Arwa A. Al-Qahtani, Fatimah S. Alhamlan, Ahmed Ali Al-Qahtani, Ahmed Ali Al-Qahtani
Abstract
Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress excessive inflammation and promote tissue repair. Here, we provide a comprehensive overview of the role of pro-inflammatory and anti-inflammatory ILs in infectious diseases, with a focus on the mechanisms underlying their effects, their diagnostic and therapeutic potential, and emerging trends in IL-based therapies.
Topics & Concepts
InflammationImmune systemImmunologyMedicineInflammatory responseInterleukinAnti-inflammatoryCytokineInflammasome and immune disordersImmune Response and InflammationImmune Cell Function and Interaction