Synthesis, biological evaluation, and in silico studies of potential activators of apoptosis and carbonic anhydrase inhibitors on isatin-5-sulfonamide scaffold
Stepan K. Krymov, Alexander M. Scherbakov, Diana I. Salnikova, Danila V. Sorokin, Lyubov G. Dezhenkova, И. В. Иванов, Daniela Vullo, Viviana De Luca, Clemente Capasso, Claudiu T. Supuran, Andrey E. Shchekotikhin
Topics & Concepts
ChemistryIsatinCarbonic anhydraseSulfonamideCarbonic anhydrase IICarbonic Anhydrase IActive siteBiochemistryEnzymeDocking (animal)Activator (genetics)ApoptosisGene isoformStereochemistryReceptorOrganic chemistryGeneNursingMedicineEnzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and Activities