Litcius/Paper detail

Design and synthesis of hederagenin derivatives modulating STING/NF-κB signaling for the relief of acute liver injury in septic mice

Tao Yu, Haoran Cheng, Xiaoli Li, Wentao Huang, Haixia Li, Xiaojin Gao, Jianing Zhao, Xin Zhang, Xiaoxiao Gu, Yi Bi, Leiming Zhang

2022European Journal of Medicinal Chemistry22 citationsDOI

Topics & Concepts

StingIn vivoPharmacologySepsisChemistryInflammationLipopolysaccharideNF-κBIκBαIn vitroSignal transductionImmunologyMedicineBiochemistryBiologyEngineeringBiotechnologyAerospace engineeringinterferon and immune responsesImmune Response and InflammationInflammasome and immune disorders