Rh(III)-Catalyzed Oxidative C–2 Coupling of <i>N</i>-Pyridinylindoles with Benzo[<i>b</i>]thiophene 1,1-Dioxides via C–H Bond Activation
Subramani Kumaran, Kanniyappan Parthasarathy
Abstract
An efficient Rh(III)-catalyzed cross-dehydrogenative coupling of N-pyridinylindoles with benzo[b]thiophene 1,1-dioxides has been developed through directing-group-assisted C–H activation. This transformation constructs a new C–C bond from two inert C–H bonds in a one-pot reaction. The present reaction is compatible with various functional groups with respect to indoles and benzothiophene[b] 1,1-dioxides. Furthermore, the emission properties of synthesized compounds have been explored.
Topics & Concepts
BenzothiopheneChemistryThiopheneCatalysisOxidative phosphorylationOxidative coupling of methaneMedicinal chemistryFunctional groupCoupling reactionStereochemistryCombinatorial chemistryOrganic chemistryPolymerBiochemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsSulfur-Based Synthesis Techniques