High-frequency electroacupuncture improves endometrial receptivity via regulating cell adhesion molecules and leukemia inhibitory factor / signal transducer and activator of transcription signaling pathway
Fang You, Xin Du, Taiwei Zhang, Yang Wang, Yuxia Lv, Li Zeng
Abstract
High-frequency electroacupuncture could effectively improve endometrial receptivity and blastocyst implantation amount in COH rats.Electroacupuncture, especially high-frequency electroacupuncture, could significantly increase endometrial thickness and the number of pinopodes.High-frequency electroacupuncture significantly reduced the protein expression levels of E-cadherin, β-catenin and CLDN1 adhesion molecules in COH rats.High-frequency electroacupuncture could markedly enhance the LIF/STAT3 signaling pathway in COH rats.
Topics & Concepts
ElectroacupunctureLeukemia inhibitory factorBlastocystInternal medicineEndometriumSTAT3EndocrinologyHuman chorionic gonadotropinMedicineControlled ovarian hyperstimulationAndrologySignal transductionInterleukin 6CytokineBiologyEmbryoHormoneCell biologyEmbryogenesisIn vitro fertilisationPathologyAcupunctureAlternative medicineReproductive System and PregnancyEndometriosis Research and TreatmentMenstrual Health and Disorders