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Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty

Oscar Junhong Luo, Wen Lei, Guodong Zhu, Zhiyao Ren, Yudai Xu, Chanchan Xiao, Hongyi Zhang, Junxiang Cai, Zhiping Luo, Lijuan Gao, Jun Su, Lei Tang, Wei Guo, Huanxing Su, Zhang‐Jin Zhang, Evandro Fei Fang, Yijun Ruan, Sean X. Leng, Zhenyu Ju, Huiling Lou, Junling Gao, Nan Peng, Jie Chen, Zhijun Bao, Feng Liu, Guobing Chen

2022Nature Aging144 citationsDOI

Topics & Concepts

Immune systemTranscriptomeBiologyPhenotypeCellImmunologyGene expression profilingGeneComputational biologyGene expressionGeneticsFrailty in Older AdultsSingle-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms
Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty | Litcius