Tetrabutylammonium bromide-based hydrophobic deep eutectic solvent for the extraction and separation of dihydromyricetin from vine tea and its inhibitory efficiency against xanthine oxidase
Liling Wang, Yanbin Wang, Meixu Chen, Yaoyao Zhu, Yuchuan Qin, Yifeng Zhou
Abstract
. The inhibitory mechanisms of DMY on XO were explored by enzyme kinetics, spectroscopy, molecular docking and molecular dynamics analysis approaches, which provided a theoretical basis for the above inhibition assays.
Topics & Concepts
Extraction (chemistry)ChromatographyChemistryFourier transform infrared spectroscopySolventResponse surface methodologyNuclear chemistryOrganic chemistryChemical engineeringEngineeringMedicinal plant effects and applicationsVanadium and Halogenation ChemistryGout, Hyperuricemia, Uric Acid