Anion Controlled Stereodivergent Semi‐Hydrogenation of Alkynes using Water as Hydrogen Source
Kangkui Li, Chunhui Yang, Jingchao Chen, Chunxiang Pan, Ruifeng Fan, Yongyun Zhou, Luo Yang, Dajian Yang, Baomin Fan
Abstract
Abstract An anion controlled stereodivergent semi‐hydrogenation of alkynes is reported. The reactions are catalyzed by the low‐cost and stable nickel(II) salts, using water as environmental friendly hydrogen source with zinc powder as metal reductant. Interestingly, the stereoselectivity of the reaction is well controlled by the anion of the nickel(II) salt. The present methodology allowed a low‐cost and convenient preparation of trans ‐ and cis ‐alkenes under mild conditions. The reaction mechanism is proposed with water as the hydrogen donor on the basis of the control experiments.
Topics & Concepts
ChemistryNickelStereoselectivityHydrogenCatalysisSalt (chemistry)ZincCombinatorial chemistryIonReaction conditionsMetalOrganic chemistryAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsNanomaterials for catalytic reactions