ApoE-mediated systemic nanodelivery of granzyme B and CpG for enhanced glioma immunotherapy
Jingjing Wei, Di Wu, Yu Shao, Beibei Guo, Jingjing Jiang, Jian Chen, Jinping Zhang, Fenghua Meng, Zhiyuan Zhong
Topics & Concepts
Granzyme BGliomaImmunotherapyCytotoxic T cellCancer researchMedicineImmunologyPericyteCpG OligodeoxynucleotideDendritic cellTumor microenvironmentImmune systemMicrogliaT cellBiologyIn vitroEndothelial stem cellInflammationGene expressionGeneDNA methylationBiochemistryGlioma Diagnosis and TreatmentNanoplatforms for cancer theranosticsImmune cells in cancer